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PERSERIS: One subcutaneous injection, once a month1

Table comparing dosing schedules of PERSERIS and other leading therapies for adult schizophrenia.

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This table shows the dosing schedule of 6 different injectable therapies for adults with schizophrenia, over a 6-week period. PERSERIS is shown to require an injection at Weeks 1 and 5, with no loading dose or oral supplementation recommended. INVEGA SUSTENNA is shown to require an injection at Week 1, followed by a second injection dose on Day 8, and a third injection at Week 6. RISPERDAL CONSTA is shown to require injections every 2 weeks at Weeks 1, 3, and 5 and should be accompanied by oral RISPERDAL (or another antipsychotic) with the first injection and continued daily for 3 weeks. ARISTADA is shown to require injections at Weeks 1 and 5, and should be accompanied by oral aripiprazole with the first injection and continued daily for 3 weeks. ARISTADA INITIO is shown to require injections at Weeks 1 and 5, including the first ARISTADA injection administered on the same day or up to 10 days after ARISTADA INITIO and 1 dose of oral aripiprazole. ABILIFY MAINTENA is shown to require injections at Weeks 1 and 5, and should be accompanied by oral aripiprazole after the first injection and continued daily for 2 weeks.

  • Prior to starting PERSERIS, establish tolerability with oral risperidone in risperidone-naive patients1
  • Patients who are on stable oral risperidone doses lower than 3 mg/day or higher than 4 mg/day may not be candidates for PERSERIS1
  • PERSERIS has not been studied in patients with renal or hepatic impairment and should be used with caution in these special populations1
  • Patients can achieve peak plasma levels of risperidone within 4 to 6 hours, and a second peak occurs after 10 to 14 days1†